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Writer's pictureHillary Meisner

The Hidden Benefit Of Exercise You’ve Probably Never Heard Of



Have you ever heard of Hope Molecules? Me neither until I was scrolling through social and came across a reel highlighting them and thought, is this really a thing?!


Well, indeed, they are.


They are biochemical messengers released during physical activity and are known to manage stress and enhance your mood. Interestingly, these molecules will also significantly impact insulin sensitivity. Let's dive deeper into this exciting research and its implications for your health.


What Are Hope Molecules?

The term 'hope molecules' is derived from a ground-breaking 2014 study that highlighted the role of proteins released by muscles during exercise, known as myokines [1]. This study revealed that these myokines have the power to influence symptoms related to mood disorders and foster resilience against stress. As you engage in physical activity, your contracting muscles release these hope molecules into your bloodstream. From there, they travel to your brain and help to mitigate stress, promoting a sense of overall well-being. (Science is pretty cool, right!)


The Link to Insulin Sensitivity.

While hope molecules' mood-boosting properties have been well-documented [2], their role in insulin sensitivity is a newer area of exploration [3]. When you exercise, the consequent release of hope molecules decreases stress levels. This is a crucial development as stress can trigger cortisol release, a hormone known to increase blood sugar levels and thus contribute to insulin resistance.


In addition, exercises, especially resistance or strength training, directly help reduce insulin resistance by making your body more efficient at processing glucose [3]. This dual action, reducing stress and enhancing glucose processing, places exercise and hope molecules at the forefront of strategies for improving insulin sensitivity.


Ways to Increase Hope Molecules

Given the benefits, it's only natural to want to increase the presence of hope molecules. And the good news? It's relatively straightforward: incorporate more resistance or strength training into your lifestyle [3]. Simple, at-home exercises with your body weight or inexpensive resistance bands can do the trick.


Practical Tips for Improving Insulin Sensitivity

While increasing hope molecule levels play a part, other factors significantly contribute to improving insulin sensitivity. Making conscious dietary choices like reducing added sugars and choosing complex carbohydrates over simple ones, gradual and sustainable lifestyle and habit changes, along with regular resistance training all cumulatively reduce insulin resistance


Understanding hope molecules and exercise's role in improving insulin sensitivity provides yet another compelling reason to maintain an active lifestyle. Remember, even small steps can cause significant health improvements over time. Whether it's incorporating resistance training, making healthier food choices, or other lifestyle modifications, every effort contributes to a healthier, happier you.


Ready to harness the power of your hope molecules? Book a free consultation with me to create a personalized path for your unique needs.


Please note: This blog post is intended for informational purposes only and should not replace professional medical advice. Always consult with a healthcare professional before starting any new exercise or nutrition program.



1. Pedersen, B. K., & Febbraio, M. A. (2008). Muscle as an endocrine organ: focus on muscle-derived interleukin-6. Physiological Reviews, 88(4), 1379-1406. Link

2. Dinas, P. C., Koutedakis, Y., & Flouris, A. D. (2011). Effects of exercise and physical activity on depression. Irish Journal of Medical Science, 180(2), 319–325. Link

3. Holten, M. K., Zacho, M., Gaster, M., Juel, C., Wojtaszewski, J. F., & Dela, F. (2004). Strength training increases insulin-mediated glucose uptake, GLUT4 content, and insulin signaling in skeletal muscle in patients with type 2 diabetes. Diabetes, 53(2), 294-305. Link




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